Background: Widespread usage of assisted reproductive technologies (ART) has led to a rise in twin pregnancies worldwide. Monochorionic placentation leads to a higher risk for fetus and mother compared to singletons and dichorionic twins, moreover placental anastomoses have the potential to cause pathologies like feto-fetal transfusion syndrome (FFTS).
Aims: This study is devoted to the presentation of complication rates, maternal and perinatal data of monochorionic diamniotic twin pregnancies and examines differences between pregnancies of spontaneous and assisted conception.
Methods: The data of the study population consisting of 199 monochorionic twin pregnancies supervised at the Department of Obstetrics and Feto-maternal Medicine at the Medical University of Vienna between 2003 and 2014 were used to create this retrospective data analysis. The medical software ViewPoint was used for documentation and research of data, the statistical analysis was conducted with the statistics software SPSS.
Results: The data of 172 spontaneously conceived pregnancies und 27 assisted pregnancies was obtained and examined. FFTS occurred in 30 cases, the difference between study groups was not significant. Women pregnant after ART treatment were significantly older (p<0,05) and more often nulliparious (p<0,01). Twins after assisted conception were born significantly more often before the 34th week of pregnancy(p<0,05). There was no significant difference in any other of the examined variables. The overall perinatal fetal mortality was 5,3%.
Conclusion: Assisted conception does not contribute to a higher risk of FFTS, intrauterine growth restriction and other pathologies, it does however lead to a higher frequency in births before the 34th week of pregnancy.