Bibliographic Metadata

Chlamydien im Kindes- und Jugendalter : - eine retrospektive Datenanalyse / eingereicht von Katharina Becher
Additional Titles
Chlamydia in childhood and adolescence-a retrospective data analysis
AuthorBecher, Katharina
Thesis advisorDörfler, Daniela
Description61 Blatt
Institutional NoteMedizinische Universität Wien, Diplomarb., 2018
Abweichender Titel laut Übersetzung der Verfasserin/des Verfassers
Date of SubmissionAugust 2018
Document typeThesis (Diplom)
Keywords (DE)Chlamydien im Kindes- und Jugendalter / sexueller Missbrauch / STD
Keywords (EN)Chlamydia trachomatis / children and adolescents / sexual abuse / sexual transmitted disease
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Abstract (German)

Hintergrund: Chlamydia trachomatis gehört zu den häufigsten Bakterien, die im Rahmen des Geschlechtsverkehrs übertragen werden können, wovon typischerweise Frauen zwischen 16 und 25 Jahren betroffen sind. Bei Kindern und Jugendlichen sollte eine Chlamydieninfektion vorrangig immer mit sexuellem Missbrauch in Zusammenhang gebracht werden, wobei auch andere Infektionsursachen berücksichtigt werden sollten.

Studienziel: Primär war zu klären, ob ein Unterschied in der Prävalenz an Chlamydieninfektionen zwischen den Patietinnenkohorten der Missbrauchsopfer und der gesunden, sich symptomatisch präsentierenden Mädchen bei den

Abstract (English)

Background: Chlamydia trachomatis is one of the most common bacteria that can be transmitted during sexual intercourse. which typically affects women between the ages of 16 and 25 years. In children and adolescents, a chlamydia infection should always be associated with sexual abuse, but other causes of infection should also be considered.

Study aim: The primary question to be answered was whether there was a difference in the prevalence of chlamydial infections between the female patient cohorts of abuse victims and the healthy, symptomatically presenting girls in the 0-13.99- and 14-19-year-old girls. In addition, it was analyzed whether coinfection by N. gonorrhoeae, T. pallidum, Hep. B or HIV was present, with which symptoms they were present in the outpatient department, whether previous illnesses or allergies could be evaluated by patient history, if the first mensturation has already started and with what antibiotics the infected girls were treated.

Methodology: The study is a retrospective monocentric data analysis that included 177 female patients between the ages of 0-19 years, considering a positive or negative chlamydial swab. Data were generated throughout the observation period from 2003 until 2016 in the outpatient clinic of the childrens gynagolocical department, general hospital AKH Vienna. To clarify the main question, contingency tables and chi-square tests were consulted on the two-sided significance level of = 0.05, while crosstalk tables were drawn up to examine the sub-question.

Results: There was no difference in the distribution between the two groups of patients with regard to chlamydia prevalence, the test value was not significant with 2 (corrected by Fisher) = 0.294, p = .755 (unilaterally). The relative risk odds ratio (OR) was 1,037 [95% CI: 1,007; 1.067] shows a slightly increased risk of chlamydia infection in abuse victims, illustrating the relevance of chlamydia screening after sexual abuse. Within the group of abuse victims, a proportion of the chlamydia infection rate could be determined to be 3.55% (95% CI [0.76, 6.34%]). In addition, the coinfection rate of 16.7% with N. gonhorrhoae corresponded to the overall test result (p = .036) and that the rate for vulvitis was much higher (12.2%) in younger patients (p = .012).

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