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Titel
Use of beta-blocker is associated with lower mortality in patients with coronary artery disease with or without COPD
Verfasser / VerfasserinWolzt, Michael ; Sheikh Rezaei, Safoura ; Rinner, Christoph ; Ratajczak, Paulina ; Grossmann, Wilfried ; Gall, Walter
Erschienen in
The Clinical Respiratory Journal, 2018, Jg. 12, H. 12, S. 2627-2634
ErschienenWiley-Blackwell, 2018
SpracheEnglisch
DokumenttypAufsatz in einer Zeitschrift
Schlagwörter (EN)betablocker / CAD / COPD / drug utilization / mortality / pharmacoepidemiology
URNurn:nbn:at:at-ubmuw:3-452 Persistent Identifier (URN)
DOI10.1111/crj.12968 
Zugriffsbeschränkung
 Das Werk ist frei verfügbar
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Use of beta-blocker is associated with lower mortality in patients with coronary artery disease with or without COPD [0.37 mb]
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Zusammenfassung (Englisch)

Introduction

Betablockers are indicated for secondary prevention of coronary artery disease (CAD). However, in patients with comorbidity of chronic obstructive pulmonary disease (COPD) an underuse of betablocker has been reported.

Materials and Methods

Prescription and demographic data and information on hospital discharge diagnoses from 13 Austrian health insurance funds for the years 20062007 were analyzed. The primary end point was allcause mortality of patients with CAD with or without COPD and its association with use of betablockers.

Results

In 2006 and 2007, 65717 patients (37% female, 63% male) were discharged with a diagnosis of CAD. Among these patients, 46% had a codiagnosis of COPD, 24% had diabetes, and 75% received betablockers. Use of betablockers was comparable in CAD patients with COPD and without COPD with 77% and 74%, respectively.

Thousand eight hundred seventytwo (8.1%) and 1473 (5.6%) patients with and without COPD, who used betablockers died within months in 2006 and 2007. Thousand five hundred fiftythree (22.0%) and 1862 (22.2%) of patients with and without COPD and without betablockers died during the corresponding time period.

Discussion

Use of betablockers was similar in patients with CAD with or without codiagnosis of COPD. However, mortality of betablocker users was markedly lower than that of nonusers in patients with CAD with or without COPD.

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CC-BY-Lizenz (4.0)Creative Commons Namensnennung 4.0 International Lizenz