Zur Seitenansicht
 

Titelaufnahme

Titel
Viral entry pathways : the example of common cold viruses
Verfasser / VerfasserinBlaas, Dieter
Erschienen in
Wiener Medizinische Wochenschrift, 2016, Jg. 166, H. 7-8, S. 211-226
ErschienenSpringer, 2016
SpracheEnglisch
DokumenttypAufsatz in einer Zeitschrift
Schlagwörter (EN)Endocytosis / Rhinovirus / Genome release / Lysosome / Uncoating
URNurn:nbn:at:at-ubmuw:3-1253 Persistent Identifier (URN)
DOI10.1007/s10354-016-0461-2 
Zugriffsbeschränkung
 Das Werk ist frei verfügbar
Dateien
Viral entry pathways [1.46 mb]
Links
Nachweis
Klassifikation
Zusammenfassung (Englisch)

For infection, viruses deliver their genomes into the host cell. These nucleic acids are usually tightly packed within the viral capsid, which, in turn, is often further enveloped within a lipid membrane. Both protect them against the hostile environment. Proteins and/or lipids on the viral particle promote attachment to the cell surface and internalization. They are likewise often involved in release of the genome inside the cell for its use as a blueprint for production of new viruses. In the following, I shall cursorily discuss the early more general steps of viral infection that include receptor recognition, uptake into the cell, and uncoating of the viral genome. The later sections will concentrate on human rhinoviruses, the main cause of the common cold, with respect to the above processes. Much of what is known on the underlying mechanisms has been worked out by Renate Fuchs at the Medical University of Vienna.

Statistik
Das PDF-Dokument wurde 2 mal heruntergeladen.
Lizenz
CC-BY-Lizenz (4.0)Creative Commons Namensnennung 4.0 International Lizenz